Kidney Failure & Heartburn Drugs

July 2016

Kidney Failure - Cautionary News

Many men with heartburn, peptic ulcers and indigestion take drugs called Proton Pump Inhibitors (PPIs) to reduce gastric acid production. Their names are listed below.

A research team in the USA looked at 20,000 men newly started on PPIs compared with 173,000 on alternative drugs. Over 5 years' follow-up 30% of men on regular PPI medication developed chronic kidney disease with the likelihood increasing with the highest doses and longest duration of treatment. The answer is for men on PPIs to consider alternatives and have their kidney function (serum creatinine) checked every year.

PPIs
Generic Name Propriety Name(s)
Esomprazole Nexium
Lansoprazole Zoton
Omeprazole Losec
Pantoprazole Protium